Lynparza-Avastin Maintenance Delays Progression of Ovarian Cancer

Results from the phase III PAOLA-1 clinical trial in women with advanced ovarian cancer evaluating maintenance therapy with Lynparza160olaparib plus Avastin bevacizumab compared to Avastin alone in women with or without BRCA gene mutations have been relea [...]

FDA Orders Allergan to Recall Textured Breast Implants Over Cancer Risk

The US Food and Drug Administration FDA has requested that Allergan recall its BIOCELL textured breast implants due to a risk of breast implant-associated anaplastic large cell lymphoma BIA-ALCL according to an announcement from the agency Although the ov [...]

Inherited pancreatic cancer risk mutation identified

Scientists have found a rare inherited gene mutation that raises the risk of pancreatic cancer and other malignancies In the future individuals with a strong family history of pancreatic cancer could be tested to determine if they carry the mutation Scien [...]

Vaccine for Acute Myeloid Leukemia?

A personalized cancer vaccine markedly improved outcomes for patients suffering from acute myeloid leukemia AML a potentially lethal blood cancer in a clinical trial led by investigators at Beth Israel Deaconess Medical Center BIDMC The product of a long- [...]

FDA approves darolutamide for non-metastatic castration-resistant prostate cancer

FDA approves darolutamide for non-metastatic castration-resistant prostate cancer On July 30 2019 the Food and Drug Administration approved darolutamide NUBEQA Bayer HealthCare Pharmaceuticals Inc for non-metastatic castration-resistant prostate cancer Ap [...]

Dana-Farber Opens New Clinical Trials for Patients with Endometrial Cancer

A recent dearth of clinical trials of treatments for endometrial cancer has segued into a research revival including four new trials led by Dana-Farber investigators spurred by advances in the scientific understanding of the disease The trials are espec [...]

FDA Approves Ruxience Biosimlar to Rituxan

The FDA approved rituximab-pvvr a rituximab biosimilar for use alone or in combination with chemotherapy for the treatment of adults with CD20-positive B-cell non-Hodgkin lymphoma NHL and chronic lymphocytic leukemia CLL as well as granulomatosis with pol [...]

FDA grants breakthrough therapy designation to Keytruda-Lenvima combination for hepatocellular carcinoma

The FDA granted breakthrough therapy designation to pembrolizumab in combination with lenvatinib as first-line treatment for patients with advanced unresectable hepatocellular carcinoma who are not able to receive locoregional treatment This is the third [...]

Bladder Cancer Advocacy Network Announces 2019 Bladder Cancer Research Innovation Awardee

July 8 2019 Bethesda MD Today the Bladder Cancer Advocacy Network BCAN announced the recipient of its prestigious Bladder Cancer Research Innovation Award160 This years awardee is Philip Beachy PhD Professor of Urology and of Developmental Biology at the [...]

Mouthwash reduces radiation-induced oral mucositis pain among patients with head and neck cancer

A mouthwash consisting of diphenhydramine lidocaine and antacids significantly reduces oral mucositis pain when used in patients receiving radiation therapy for the treatment of head and neck cancer 160 Researchers assigned 275 patients with head and neck [...]