AMG 386 Shows Promise Against Recurrent Ovarian Cancer

In a Phase II clinical trial among women with recurrent ovarian cancer, the investigational targeted therapy AMG 386 produced promising response rates when used in combination with paclitaxel. These results were presented at the 35th European Society for Medical Oncology (ESMO) Congress. Many women treated for ovarian cancer will eventually experience a recurrence of their […]

Continued Chemotherapy in Advanced Ovarian Cancer

Continuing chemotherapy following initial treatment of advanced ovarian cancer may improve survival, according to a study published in Cancer. Ovarian cancer has the highest mortality rate of all gynecologic cancers. It is the fifth leading cause of cancer death among U.S. women, with an estimated 21,550 new cases and 14,600 deaths in 2009. Treatment for […]

Farletuzumab Shows Promise in Relapsed Ovarian Cancer

According to the results of a Phase II clinical trial, the investigational drug farletuzumab may have anticancer activity in the treatment of relapsed ovarian cancer when combined with chemotherapy. These results were presented at a European cancer conference. Many women treated for ovarian cancer will eventually experience a return (relapse) of their cancer. Outcomes remain […]

Number of Obesity-related Cancers Is Growing

In 2008, excess body weight was responsible for over 124,000 new cancer diagnoses in Europe. These results were presented at a major European cancer conference. Obesity is increasingly being recognized as a risk factor not only for cancer development, but also for worse outcomes after cancer treatment. Links between obesity and endometrial cancer, postmenopausal breast […]

Women Report Symptoms Prior to Diagnosis of Ovarian Cancer

Women commonly report symptoms to their primary care provider during the year before a diagnosis of ovarian cancer. The results of this study, which was conducted in the UK, were published in the British Medical Journal. Ovarian cancer has the highest mortality rate of all gynecologic cancers. It is the fifth leading cause of cancer […]

September Is National Ovarian Cancer Awareness Month

As the month of September brings ovarian cancer into focus, it’s time to increase public understanding about the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated ovarian cancer information throughout the year. According to statistics from the American Cancer Society (ACS), ovarian cancer causes more deaths than […]

Many High-risk Women Opt for Preventive Removal of Breasts and Ovaries

Many women who are considered to be at high risk for developing breast or ovarian cancer are choosing to undergo preventive mastectomy (removal of breasts) and/or oophorectomy (removal of ovaries) in order to reduce their risk of developing the disease, according to a study published in Cancer Epidemiology, Biomarkers, & Prevention. Inherited mutations in two […]

Fertility Preservation Appears to Be Safe for Young Women with Early-stage Ovarian Cancer

Preservation of the non-cancerous ovary and the uterus appears to be safe for young women with Stage IA or IC ovarian cancer and allows women to preserve their fertility. These results were published in Cancer. Women who confront a cancer diagnosis at a young age often must consider how cancer treatment will affect their ability […]

False-positive Results Are Common with Cancer Screening

The risk of obtaining a false-positive result from screening for prostate, lung, colorectal, and ovarian cancer is high and becomes cumulatively higher with ongoing screening—after 14 screening tests, the cumulative risk of a false-positive is 60.4% for men and 48.8% for women, according to the results of a study published in the Annals of Family […]

Hormone Therapy Increases Ovarian Cancer Risk

Women who use postmenopausal hormones have an increased risk of developing ovarian cancer, according to a study conducted in Denmark. These results were published in the Journal of the American Medical Association. Estrogen, with or without progestin, is an effective treatment for many menopausal symptoms. During the last several years, however, studies have raised concerns […]