Cervarix Provides Cross-Protection Against Other Types of HPV

Updated results from a large clinical trial of the HPV vaccine Cervarix® (human papillomavirus bivalent [types 16 and 18] recombinant vaccine) confirm its protection against cervical precancer and cancer and also provide evidence of cross-protection against other high-risk types of HPV. These results were published in Lancet Oncology. Human papillomaviruses (HPV) consist of more than 100 [...]

DES Daughters Have Increased Risk of Cancer

According to a study published in the New England Journal of Medicine, women exposed to diethylstilbestrol (DES) before birth have an increased risk of vaginal cancer, cervical precancers, and breast cancer. These women also have an increased risk for a wide range of reproductive problems. Diethylstilbestrol is a synthetic estrogen that was prescribed to pregnant [...]

Chemotherapy During Pregnancy Not Linked with Developmental Problems in Kids

According to a study presented at the 2011 European Multidisciplinary Cancer Congress, children born to women who received chemotherapy during pregnancy do not appear to have an increased risk of heart or cognitive problems. Since relatively few women are diagnosed with cancer during pregnancy, data regarding the effects of chemotherapy during pregnancy are limited. Determining [...]

Study Tracks Global Trends in Breast and Cervical Cancer

A study of trends in breast and cervical cancer in 187 countries reports that worldwide, the number of new breast cancer cases increased from about 641,000 cases in 1980 to 1.6 million cases in 2010. These results were published in The Lancet. Among women in the United States, breast cancer is the most commonly diagnosed [...]

IUDs May Reduce Risk of Cervical Cancer

In a combined analysis of several previous studies, women who used intrauterine devices (IUDs) had a 45% reduction in risk of cervical cancer. These results were published in Lancet Oncology. The most important cause of cervical cancer is infection with a high-risk type of human papillomavirus (HPV). Human papillomaviruses consist of a group of more [...]

Repeated HPV Tests Provide Information about Cervical Cancer Risk

Among women over the age of 30 who test positive for a high-risk type of human papillomavirus (HPV) but have no apparent cervical abnormalities, a repeat HPV test two years later provides information about cervical cancer risk: women with an HPV infection that persists have a substantially increased risk for cervical cancer. These results were [...]

Many Teens Not Vaccinated Against HPV

Only about half of US teen girls have been vaccinated against the forms of human papillomavirus (HPV) that are associated with cervical cancer. These findings were recently reported in the Centers for Disease Control and Prevention’s (CDC) Morbidity and Mortality Weekly Report. Human papillomaviruses (HPV) consist of more than 100 different viruses. Some types of HPV [...]

Clinical Trial Participation Is Inadequate

A large proportion of cancer patients do not enroll in clinical trials, and those who do participate may not adequately represent age groups, cancer stages, cancer types, and racial and ethnic groups. These findings were recently reported in the Annals of Surgery. Clinical trials are the process through which medications ultimately become approved by the [...]

Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain

Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does reduce recurrence of brain metastases. These findings were recently published in the Journal of Clinical Oncology.[1] One common [...]

Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment

A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently published in the journal Cancer.[1] Lymphedema is the buildup of lymph fluid in the tissues just under the [...]