Mark R. Hutchins, M.D.   I   Daniel F. Moravec, Jr., M.D.   I   Joni A. Tilford, M.D.   I   Madhu V. Midathada, M.D.
 
Colon Cancer

Antibiotic Sponge Ineffective at Preventing Surgical Infection (08/12/2010)
Patients undergoing colorectal surgery are reported to experience an increased incidence of surgical-site infection with the addition of a gentamicin-collagen sponge enclosed at the surgery site. These findings were recently published in the New England Journal of Medicine.

Screening Rates Among Older Americans (07/15/2010)
More older Americans are undergoing screening for colon cancer, but the rates for breast cancer screening remain the same, according to a government report released on July 6, 2010.

Radioembolization plus Fluorouracil Active in Colorectal Cancer Patients with Liver Metastases (07/02/2010)
Radioembolization plus the chemotherapy agent fluorouracil slows cancer progression for colorectal cancer patients whose disease has progressed following prior treatment with chemotherapy and have metastases limited to the liver.

Potential Role for Oncotype DX Colon Cancer Test in Stage III Cancer (06/10/2010)
The Oncotype DX® colon cancer test, which is currently available for treatment planning in Stage II colon cancer, may also predict recurrence risk in Stage III colon cancer. These results were presented at the 2010 annual meeting of the American Society of Clinical Oncology.

Erbitux Does Not Improve Survival in Stage III Colon Cancer with Normal KRAS (06/08/2010)
The addition of Erbitux® (cetuximab) to standard adjuvant chemotherapy in patients with stage III colon cancer who have normal KRAS gene activity does not improve survival, according to the results of a Phase III study presented at the 2010 annual meeting of the American Society of Clinical Oncology.

Depression May Persist With Metastatic Cancer (05/27/2010)
A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.


Latest Colon Cancer by Stage
Adjuvant (I-III, A-C)

Antibiotic Sponge Ineffective at Preventing Surgical Infection (08/12/2010)
Patients undergoing colorectal surgery are reported to experience an increased incidence of surgical-site infection with the addition of a gentamicin-collagen sponge enclosed at the surgery site. These findings were recently published in the New England Journal of Medicine.

Potential Role for Oncotype DX Colon Cancer Test in Stage III Cancer (06/10/2010)
The Oncotype DX® colon cancer test, which is currently available for treatment planning in Stage II colon cancer, may also predict recurrence risk in Stage III colon cancer. These results were presented at the 2010 annual meeting of the American Society of Clinical Oncology.

Erbitux Does Not Improve Survival in Stage III Colon Cancer with Normal KRAS (06/08/2010)
The addition of Erbitux® (cetuximab) to standard adjuvant chemotherapy in patients with stage III colon cancer who have normal KRAS gene activity does not improve survival, according to the results of a Phase III study presented at the 2010 annual meeting of the American Society of Clinical Oncology.

Screening/Prevention

Screening Rates Among Older Americans (07/15/2010)
More older Americans are undergoing screening for colon cancer, but the rates for breast cancer screening remain the same, according to a government report released on July 6, 2010.

Rates of Adenoma Detection Linked to Risk of Interval Colorectal Cancer (05/18/2010)
Endoscopists who detect tumors or polyps (adenomas) at a higher rate during colonoscopy screening for colorectal cancer tend to produce a lower risk for interval cancer among their patients, according to a study published in the New England Journal of Medicine.

Stage IV (D)/Relapsed

Radioembolization plus Fluorouracil Active in Colorectal Cancer Patients with Liver Metastases (07/02/2010)
Radioembolization plus the chemotherapy agent fluorouracil slows cancer progression for colorectal cancer patients whose disease has progressed following prior treatment with chemotherapy and have metastases limited to the liver.

Depression May Persist With Metastatic Cancer (05/27/2010)
A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.

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